| Khoom npe | 2,5-dioxopyrrolidin-1-yl 4- (bis (4-chlorophenyl) pecerazine-1-carboxylate | Qauv mis |  |
| Cas Tsis tau. | 1438416-21-7 | Molecular hnyav | 462.33 |
| Kev tshwm sim | hmoov | Kub taw tes | 561.5 ± 60.0 Degree (kwv yees) |
| Lam xav | 99% | Lub thawv | 10kg; 25kg; 200KG |
| Cov lus ntawm ib txoj kab ke | C22h2Cl2n3n3N3O4 |
Daim ntawv thov
- Endocannabinoids xws li 2 {- aracidonoyl glyaclamide (2-ag;) thiab archan;) MonooCyCyLglycerol lase (Magl) yog serine hydrolase funcolase ntawm 2-ag mus rau aracidonic acid thiab glycerol, yog li txiav nws txoj haujlwm. Mjn110 yog n-hydoxysuccinimidyl carbamate uas inhibits magl (Ic {}}}}} {}> 10 μm) thiab lwm lub hlwb serine hydroccases. Nws tuaj yeem tiv thaiv 2-ag hydrolysis (ic50=2.1 nm) uas tsis muaj kev cuam tshuam rau ntawm AEA hydrolysis nce mus txog 50 μm. Ntawm 5 mg / kg, mg, mjn110 tau pom rau Alleviate tshuab almidia hauv cov qauv nas ntawm cov ntshav qab zib neuropathy. [Cayman tshuaj]
- MJN110 tau siv los ua monoacylglycerol liipase (Magl) tus neeg nyob rau hauv cov nyhuv ntawm kev tu siab ntawm nas. Nws kuj tau siv rau inhibit lipid droplet tsim kev tsim.
Kev xa mus
Cim npe nrov: Cas # 1438416-21-7|2,5-dioxoprrolidin-1-YL 4- (bis (4-chlorophenyl) piperazine-piperoxine-138416-21-7|2,5-dioxoprrolidin-1-YL 4- (bis (4-chlorophenyl) piperazine-piperazy-piperazy-piperazy-1-Carerazy-aws-1-cov neeg muag khoom, cov chaw muag khoom, Hoobkas
